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Figure 2 | BMC Anesthesiology

Figure 2

From: Design and Organization of the Dexamethasone, Light Anesthesia and Tight Glucose Control (DeLiT) Trial: a factorial trial evaluating the effects of corticosteroids, glucose control, and depth-of-anesthesia on perioperative inflammation and morbidity from major non-cardiac surgery

Figure 2

Stopping boundaries for efficacy and futility. Plot of the standardized treatment effect (z- statistic) on vertical axis and accrued sample size on the horizontal axis, where a z-statistic of zero indicates no treatment effect. Outside shaded regions indicate sufficient evidence to reject null hypothesis for efficacy (top) or harm (below), while inside shaded region indicates evidence to stop for futility, or no effect.

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