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  1. Research article

    Comparison of the myocardial protective effect of sevoflurane versus propofol in patients undergoing heart valve replacement surgery with cardiopulmonary bypass

    This study aimed to compare myocardial protective effects of anaesthesia with intravenous infusion of propofol versus inhalation of sevoflurane in patients undergoing heart valve replacement surgery with cardi...

    Xiao-Lin Yang, Dan Wang, Guo-Yuan Zhang and Xiao-Lan Guo

    BMC Anesthesiology 2017 17:37

    Published on: 4 March 2017

  2. Research article

    Effect of Dexmedetomidine combined with sufentanil for post- thoracotomy intravenous analgesia:a randomized, controlled clinical study

    Few studies have investigated the use of dexmedetomidine in patient-controlled intravenous analgesia (PCIA) after thoracic surgery. This study to evaluate the effect of dexmedetomidine combined with sufentanil...

    Chun-Shan Dong, Jun Zhang, Qiang Lu, Peng Sun, Jun-Ma Yu, Chao Wu and Hao Sun

    BMC Anesthesiology 2017 17:33

    Published on: 1 March 2017

  3. Research article

    The protective effects of propofol against CoCl2-induced HT22 cell hypoxia injury via PP2A/CAMKIIα/nNOS pathway

    Perioperative cerebral ischemia/hypoxia could induce hippocampal injury and has been reported to induce cognitive impairment. In this study, we used cobalt chloride (CoCl2) to build a hypoxia model in mouse hippo...

    Yan Lu, Wei Chen, Chen Lin, Jiaqiang Wang, Minmin Zhu, Jiawei Chen and Changhong Miao

    BMC Anesthesiology 2017 17:32

    Published on: 28 February 2017

  4. Research article

    Magnesium sulphate attenuate remifentanil-induced postoperative hyperalgesia via regulating tyrosine phosphorylation of the NR2B subunit of the NMDA receptor in the spinal cord

    Remifentanil induced hyperalgesia (RIH) is characterized by stimulation evoked pain including allodynia and thermal hyperalgesia after remifentanil infusion. N-methyl-D-aspartate (NMDA) receptor was reported t...

    Jiehao Sun, Hai Lin, Guodong He, Wendong Lin and Jianping Yang

    BMC Anesthesiology 2017 17:30

    Published on: 21 February 2017

  5. Research article

    Administration of HES in elderly patients undergoing hip arthroplasty under spinal anesthesia is not associated with an increase in renal injury

    Hydroxyethyl starch (HES) is applied to achieve volume expansion during surgery; however, nephrotoxicity may be induced in patients with sepsis. Simultaneously, neutrophil gelatinase-associated lipocalin (NGAL...

    Yuanyuan Zhang, Yonghao Yu, Junya Jia, Wenli Yu, Rubin Xu, Licheng Geng and Ying Wei

    BMC Anesthesiology 2017 17:29

    Published on: 21 February 2017

  6. Research article

    Tracheal extubation in deeply anesthetized pediatric patients after tonsillectomy: a comparison of high-concentration sevoflurane alone and low-concentration sevoflurane in combination with dexmedetomidine pre-medication

    Dexmedetomidine can facilitate a smooth extubation process and reduce the requirement of sevoflurane and emergence agitation when administrated perioperatively. We aimed to observe the extubation process and t...

    Meiqin Di, Yuan Han, Zhuqing Yang, Huacheng Liu, Xuefei Ye, Hongyan Lai, Jun Li, Wangning ShangGuan and Qingquan Lian

    BMC Anesthesiology 2017 17:28

    Published on: 21 February 2017

  7. Research article

    The effect of deep muscle relaxation on the force required during Latissimus Dorsi dissection for breast reconstructive surgery: results of a prospective, double-blinded observational pilot study

    The use of neuromuscular blocking agents has previously been suggested to facilitate the dissection of the latissimus dorsi muscle during breast reconstructive surgery. The aim of this study was to quantify th...

    T. Ledowski, A. Goodwin-Walters, P. Quinn and M. Calvert

    BMC Anesthesiology 2017 17:27

    Published on: 21 February 2017

  8. Research article

    A comparison of the transillumination-assisted technique versus midline approach technique in novices: a prospective randomized controlled trial about the Bonfils intubation fiberscope

    The present study aimed to compare the safety and efficacy for novices to conduct intubation with the Bonfils intubation fiberscope (BIF) using the transillumination-assisted or midline approach technique in p...

    Jian Wang, Lan Yuan, Guoqiang Fu, Wei Tang, Guijie Yu, Feng Guo and Jiangang Song

    BMC Anesthesiology 2017 17:31

    Published on: 21 February 2017

  9. Research article

    A preliminary assessment of the LMA protector™ in non-paralysed patients

    The LMA Protector™ is the latest CE marked single use supraglottic airway device. This airway device provides access and functional separation of the respiratory and digestive tracts. There are two ports (male...

    Ban Leong Sng, Farida Binte Ithnin, Deepak Mathur, Eileen Lew, Nian-Lin Reena Han and Alex Tiong-Heng Sia

    BMC Anesthesiology 2017 17:26

    Published on: 20 February 2017

  10. Research article

    Is propofol injection pain really important to patients?

    Propofol injection pain (PIP) has been adequately studied during the past decades. However, patients’ opinion on this problem and the incidence of patients’ recall of this brief discomfort are still unknown. T...

    Wen Wang, Linxin Wu, Chaobin Zhang and Li Sun

    BMC Anesthesiology 2017 17:24

    Published on: 17 February 2017

  11. Research article

    Targeting urine output and 30-day mortality in goal-directed therapy: a systematic review with meta-analysis and meta-regression

    Oliguria is associated with a decreased kidney- and organ perfusion, leading to organ damage and increased mortality. While the effects of correcting oliguria on renal outcome have been investigated frequently...

    Esther N. van der Zee, Mohamud Egal, Diederik Gommers and A. B. Johan Groeneveld

    BMC Anesthesiology 2017 17:22

    Published on: 10 February 2017

  12. Research article

    A clinical score to predict mortality in septic acute kidney injury patients requiring continuous renal replacement therapy: the HELENICC score

    This study aimed to identify predictors of early (7-day) mortality in patients with septic acute kidney injury (AKI) who required continuous renal replacement therapy (CRRT).

    Rogério da Hora Passos, João Gabriel Rosa Ramos, Evandro Jose Bulhoes Mendonça, Eva Alves Miranda, Fábio Ricardo Dantas Dutra, Maria Fernanda R. Coelho, Andrea C. Pedroza, Luis Claudio L. Correia, Paulo Benigno Pena Batista, Etienne Macedo and Margarida M. D. Dutra

    BMC Anesthesiology 2017 17:21

    Published on: 7 February 2017

  13. Research article

    Plasma pro-atrial natriuretic peptide to estimate fluid balance during open and robot-assisted esophagectomy: a prospective observational study

    It remains debated how much fluid should be administered during surgery. The atrial natriuretic peptide precursor proANP is released by atrial distension and deviations in plasma proANP are reported associated...

    Rune Broni Strandby, Rikard Ambrus, Niels H. Secher, Jens Peter Goetze, Michael Patrick Achiam and Lars Bo Svendsen

    BMC Anesthesiology 2017 17:20

    Published on: 3 February 2017

  14. Research article

    Supplement of levosimendan to epinephrine improves initial resuscitation outcomes from asphyxial cardiac arrest

    Levosimendan exerted favorable effects on the initial outcome in the treatment of ventricular fibrillation cardiac arrest. This study investigated the efficacy of levosimendan in the treatment of asphyxia-indu...

    Bingjing Wu, Yong G. Peng, Shishi Zhao, Nana Bao, Linmin Pan, Jiaojiao Dong, Xuzhong Xu and Quanguang Wang

    BMC Anesthesiology 2017 17:18

    Published on: 2 February 2017

  15. Research article

    Evaluation of the optimal cuff volume and cuff pressure of the revised laryngeal tube “LTS-D” in surgical patients

    Recent case reports have indicated significant cuff overinflation when using the standard filling volume based on the manufacturer’s recommendations in older models of laryngeal tubes. The aim of this study wa...

    Marc Kriege, Christian Alflen, Johannes Eisel, Thomas Ott, Tim Piepho and Ruediger R. Noppens

    BMC Anesthesiology 2017 17:19

    Published on: 2 February 2017

  16. Research article

    Acute kidney injury induces high-sensitivity troponin measurement changes after cardiac surgery

    The value of cardiac troponin as a risk assessment tool for cardiac disease in the setting of end-stage renal diseases (ESRD) is not equivalent to its value in those with normal renal function. This considerat...

    Amr S Omar, Khaled Mahmoud, Samy Hanoura, Hany Osman, Praveen Sivadasan, Suraj Sudarsanan, Yasser Shouman, Rajvir Singh and Abdulaziz AlKhulaifi

    BMC Anesthesiology 2017 17:15

    Published on: 31 January 2017

  17. Research article

    Retrospective case-control non-inferiority analysis of intravenous lidocaine in a colorectal surgery enhanced recovery program

    Enhanced recovery after surgery (ERAS) programs typically utilizes multi-modal analgesia to reduce perioperative opioid consumption. Systemic lidocaine is used in several of these ERAS algorithms and has been ...

    Bhiken I. Naik, Siny Tsang, Anne Knisely, Sandeep Yerra and Marcel E. Durieux

    BMC Anesthesiology 2017 17:16

    Published on: 31 January 2017

  18. Research article

    Repeated remote ischemic preconditioning and isoflurane anesthesia in an experimental model of renal ischemia-reperfusion injury

    In animal studies, remote ischemic preconditioning (RIPC) and anesthetic preconditioning are successful in reducing renal ischemia reperfusion injury (IRI), however the protective effect of RIPC may be improve...

    Theo P. Menting, Mehmet Ergun, Moira H. D. Bruintjes, Kimberley E. Wever, Roger M. L. M. Lomme, Harry van Goor and Michiel C. Warlé

    BMC Anesthesiology 2017 17:14

    Published on: 28 January 2017

  19. Research article

    Feasibility of the modified sequential organ function assessment score in a resource-constrained setting: a prospective observational study

    Sub-Saharan Africa has a great burden of critical illness with limited health care resources. We evaluated the feasibility and utility of the modified Sequential Organ Function Assessment (mSOFA) score in asse...

    Cornelius Sendagire, Michael S. Lipnick, Sam Kizito, Rebecca Kruisselbrink, Daniel Obua, Joseph Ejoku, Lameck Ssemogerere, Jane Nakibuuka and Arthur Kwizera

    BMC Anesthesiology 2017 17:12

    Published on: 26 January 2017

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