Perioperative medicine and outcome

Section edited by Laura Pasin

This section considers manuscripts concerning anesthesia in the pre-, intra- and post-operative settings. Studies concerning the outcome of patients when this is related to operative anesthesia will also be considered.

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  1. Research article

    Risk factors for pulmonary complications after hepatic resection: role of intraoperative hemodynamic instability and hepatic ischemia

    Postoperative operative pulmonary complications (PPCs) after hepatic surgery are associated with increased length of hospital stays. Intraoperative blood transfusion, extensive resection and different comorbid...

    Victoria Lepere, Antoine Vanier, Yann Loncar, Louis Lemoine, Jean Christophe Vaillant, Antoine Monsel, Eric Savier, Pierre Coriat and Daniel Eyraud

    BMC Anesthesiology 2017 17:84

    Published on: 20 June 2017

  2. Research article

    Lipid emulsion mitigates impaired pulmonary function induced by limb ischemia/reperfusion in rats through attenuation of local cellular injury and the subsequent systemic inflammatory

    Limb ischemia/reperfusion causes inflammation and elicits oxidative stress that may lead to local tissue damage and remote organ such as lung injury. This study investigates pulmonary function after limb ische...

    Fangfang Xia, Yun Xia, Sisi Chen, Lulu Chen, Weijuan Zhu, Yuanqing Chen, Thomas J. Papadimos, Xuzhong Xu and Le Liu

    BMC Anesthesiology 2017 17:83

    Published on: 19 June 2017

  3. Research article

    Sensitivity to Sevoflurane anesthesia is decreased in mice with a congenital deletion of Guanylyl Cyclase-1 alpha

    Volatile anesthetics increase levels of the neurotransmitter nitric oxide (NO) and the secondary messenger molecule cyclic guanosine monophosphate (cGMP) in the brain. NO activates the enzyme guanylyl cyclase ...

    Yasuko Nagasaka, Martin Wepler, Robrecht Thoonen, Patrick Y. Sips, Kaitlin Allen, Jan A. Graw, Vincent Yao, Sara M. Burns, Stefan Muenster, Peter Brouckaert, Keith Miller, Ken Solt, Emmanuel S. Buys, Fumito Ichinose and Warren M. Zapol

    BMC Anesthesiology 2017 17:76

    Published on: 14 June 2017

  4. Research article

    Dose-dependent effects of intravenous methoxamine infusion during hip-joint replacement surgery on postoperative cognitive dysfunction and blood TNF-α level in elderly patients: a randomized controlled trial

    Postoperative cognitive dysfunction (POCD), common in elderly patients, is thought to be closely associated with intraoperative instability of hemodynamics and excessive excretion of tumor necrosis factor-α (T...

    Shenghui Sun, Defeng Sun, Lin Yang, Jun Han, Ruochuan Liu and Lijie Wang

    BMC Anesthesiology 2017 17:75

    Published on: 9 June 2017

  5. Research article

    Development and validation of a Score for Preoperative Prediction of Obstructive Sleep Apnea (SPOSA) and its perioperative outcomes

    Postoperative respiratory complications (PRCs) are associated with significant morbidity, mortality, and hospital costs. Obstructive sleep apnea (OSA), often undiagnosed in the surgical population, may be a co...

    Christina H. Shin, Stephanie D. Grabitz, Fanny P. Timm, Noomi Mueller, Khushi Chhangani, Karim Ladha, Scott Devine, Tobias Kurth and Matthias Eikermann

    BMC Anesthesiology 2017 17:71

    Published on: 30 May 2017

  6. Research article

    Does an electronic cognitive aid have an effect on the management of severe gynaecological TURP syndrome? A prospective, randomised simulation study

    Lack of familiarity with the content of current guidelines is a major factor associated with non-compliance by clinicians. It is conceivable that cognitive aids with regularly updated medical content can guide...

    Michael St.Pierre, Georg Breuer, Dieter Strembski, Christopher Schmitt and Bjoern Luetcke

    BMC Anesthesiology 2017 17:72

    Published on: 30 May 2017

  7. Research article

    A pragmatic multi-center trial of goal-directed fluid management based on pulse pressure variation monitoring during high-risk surgery

    Intraoperative fluid therapy guided by mechanical ventilation-induced pulse-pressure variation (PPV) may improve outcomes after major surgery. We tested this hypothesis in a multi-center study.

    Luiz Marcelo Sá Malbouisson, João Manoel Silva, Maria José Carvalho Carmona, Marcel Rezende Lopes, Murilo Santucci Assunção, Jorge Luís dos Santos Valiatti, Claudia Marques Simões and José Otavio Costa Auler

    BMC Anesthesiology 2017 17:70

    Published on: 30 May 2017

  8. Research article

    Combination of gabapentin and ramosetron for the prevention of postoperative nausea and vomiting after gynecologic laparoscopic surgery: a prospective randomized comparative study

    As a drug originally introduced for its anticonvulsant effects, gabapentin has been recently shown to be effective in the treatment of nausea and vomiting in various clinical settings. This study compared the ...

    Kyung Mi Kim, Jin Huh, Soo Kyung Lee, Eun Young Park, Jung Min Lee and Hyo Ju Kim

    BMC Anesthesiology 2017 17:65

    Published on: 19 May 2017

  9. Research article

    Continuous femoral nerve blockade and single-shot sciatic nerve block promotes better analgesia and lower bleeding for total knee arthroplasty compared to intrathecal morphine: a randomized trial

    Knee arthroplasty leads to postoperative pain. This study compares analgesia and postoperative bleeding achieved by intrathecal morphine with a continuous femoral plus single-shot sciatic nerve block.

    Nora Elizabeth Rojas Álvarez, Rosemberg Jairo Gomez Ledesma, Adilson Hamaji, Marcelo Waldir Mian Hamaji and Joaquim Edson Vieira

    BMC Anesthesiology 2017 17:64

    Published on: 12 May 2017

  10. Research article

    Effects of colloid pre-loading on thromboelastography during elective intracranial tumor surgery in pediatric patients: hydroxyethyl starch 130/0.4 versus 5% human albumin

    Volume replacement therapy with colloid is still worth studying in major pediatric surgery with potential risk of bleeding. This study assessed the effects of 6% hydroxyethyl starch (HES) 130/0.4 and 5% Human ...

    Yuanzhi Peng, Jianer Du, Xuan Zhao, Xueyin Shi and Yingwei Wang

    BMC Anesthesiology 2017 17:62

    Published on: 27 April 2017

  11. Research article

    Leg elevation decreases the incidence of post-spinal hypotension in cesarean section: a randomized controlled trial

    Maternal hypotension is a common complication after spinal anesthesia for cesarean section (CS). In this study we investigated the role of leg elevation (LE) as a method for prevention of post-spinal hypotensi...

    Ahmed Hasanin, Ahmed Aiyad, Ahmed Elsakka, Atef Kamel, Reham Fouad, Mohamed Osman, Ali Mokhtar, Sherin Refaat and Yasmin Hassabelnaby

    BMC Anesthesiology 2017 17:60

    Published on: 24 April 2017

  12. Research article

    Half dose sugammadex combined with neostigmine is non-inferior to full dose sugammadex for reversal of rocuronium-induced deep neuromuscular blockade: a cost-saving strategy

    Sugammadex reverses the effect of rocuronium more rapidly and effectively than neostigmine, at all levels of neuromuscular blockade (NMB). However, its cost is prohibitive. The combination of half dose sugamma...

    Marie T. Aouad, Waseem S. Alfahel, Roland N. Kaddoum and Sahar M. Siddik-Sayyid

    BMC Anesthesiology 2017 17:57

    Published on: 11 April 2017

  13. Research article

    Prediction of the optimal depth for superior vena cava cannulae with cardiac computed tomography during minimally invasive cardiac surgery: a prospective observational cohort study

    The determination of the adequate depth of superior vena cava cannulae during minimally invasive cardiac surgery is important for warranting venous drainage and preventing complications during cardiopulmonary ...

    Ji-Hyun Chin, Eun-Ho Lee, Jong-Il Kim and In-Cheol Choi

    BMC Anesthesiology 2017 17:56

    Published on: 7 April 2017

  14. Research article

    Propofol and sufentanil may affect the patients’ sleep quality independently of the surgical stress response: a prospective nonrandomized controlled trial in 1033 patients’ undergone diagnostic upper gastrointestinal endoscopy

    It is unknown whether sedative per se contributes to the postoperative sleep disturbance. Diagnostic upper gastrointestinal endoscopy (UGE) is a minimally invasive procedure which is not likely to cause tissue...

    Ming Lei, Peng Zhang, Yunfei Liu, Fangfang Fu, Ling Ye and Tao Zhu

    BMC Anesthesiology 2017 17:53

    Published on: 31 March 2017

  15. Research article

    A randomized trial of remote ischemic preconditioning and control treatment for cardioprotection in sevoflurane-anesthetized CABG patients

    Remote ischemic preconditioning (RIPC) efficacy is debated. Possibly, because propofol, which has a RIPC-inhibiting action, is used in most RIPC trials. It has been suggested that clinical efficacy is, however...

    Rianne Nederlof, Nina C. Weber, Nicole P. Juffermans, Bas A. M. J. de Mol, Markus W. Hollmann, Benedikt Preckel and Coert J. Zuurbier

    BMC Anesthesiology 2017 17:51

    Published on: 29 March 2017

  16. Research article

    The effect of an electronic cognitive aid on the management of ST-elevation myocardial infarction during caesarean section: a prospective randomised simulation study

    Cognitive aids have come to be viewed as promising tools in the management of perioperative critical events. The majority of published simulation studies have focussed on perioperative crises that are characte...

    Michael St.Pierre, Bjoern Luetcke, Dieter Strembski, Christopher Schmitt and Georg Breuer

    BMC Anesthesiology 2017 17:46

    Published on: 20 March 2017

  17. Research article

    The value of arterial pressure waveform cardiac output measurements in the radial and femoral artery in major cardiac surgery patients

    A relatively new uncalibrated arterial pressure waveform cardiac output (CO) measurement technique is the Pulsioflex-ProAQT® system. Aim of this study was to validate this system in cardiac surgery patients wi...

    A. van Drumpt, J. van Bommel, S. Hoeks, F. Grüne, T. Wolvetang, J. Bekkers and M. ter Horst

    BMC Anesthesiology 2017 17:42

    Published on: 14 March 2017

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