Critical care

Section edited by Matthias Eikermann

This section deals with all manuscripts related to critical care and ICU medicine.

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  1. Research article

    Systolic blood pressure variability in patients with early severe sepsis or septic shock: a prospective cohort study

    Severe sepsis and septic shock are often lethal syndromes, in which the autonomic nervous system may fail to maintain adequate blood pressure. Heart rate variability has been associated with outcomes in sepsis...

    Yi Tang, Jeff Sorenson, Michael Lanspa, Colin K. Grissom, V.J. Mathews and Samuel M. Brown

    BMC Anesthesiology 2017 17:82

    Published on: 17 June 2017

  2. Research article

    Effects of immunonutrition on biomarkers in traumatic brain injury patients in Malaysia: a prospective randomized controlled trial

    Head injury is one of the top three diagnosis leading to intensive care unit (ICU) admission in Malaysia. There has been growing interest in using immunonutrition as a mode of modulating the inflammatory respo...

    Vineya Rai Hakumat Rai, Lee Fern Phang, Sheau Fung Sia, Amirah Amir, Jeyaganesh S. Veerakumaran, Mustafa Kassim Abdulazez Kassim, Rafidah Othman, Pei Chien Tah, Pui San Loh, Mohamad Irfan Othman Jailani and Gracie Ong

    BMC Anesthesiology 2017 17:81

    Published on: 15 June 2017

  3. Research article

    Effect of a simulation-based workshop on breaking bad news for anesthesiology residents: an intervention study

    Breaking bad news (BBN) to patients and their relatives is a complex and stressful task. The ideal structure, training methods and assessment instruments best used to teach and assess BBN for anesthesiology re...

    Vanda Yazbeck Karam, Hanane Barakat, Marie Aouad, Ilene Harris, Yoon Soo Park, Nazih Youssef, John Jack Boulet and Ara Tekian

    BMC Anesthesiology 2017 17:77

    Published on: 14 June 2017

  4. Research article

    Moxifloxacin monotherapy versus combination therapy in patients with severe community-acquired pneumonia evoked ARDS

    We tested the hypothesis that moxifloxacin monotherapy is equally effective and safe as a betalactam antibiotic based combination therapy in patients with acute respiratory distress syndrome (ARDS) evoked by s...

    Tim Rahmel, Sven Asmussen, Jan Karlik, Jörg Steinmann, Michael Adamzik and Jürgen Peters

    BMC Anesthesiology 2017 17:78

    Published on: 14 June 2017

  5. Research article

    Association between cardiopulmonary resuscitation duration and one-month neurological outcomes for out-of-hospital cardiac arrest: a prospective cohort study

    The duration of cardiopulmonary resuscitation (CPR) is an important factor associated with the outcomes for an out-of-hospital cardiac arrest. However, the appropriate CPR duration remains unclear considering ...

    Masahiro Kashiura, Yuichi Hamabe, Akiko Akashi, Atsushi Sakurai, Yoshio Tahara, Naohiro Yonemoto, Ken Nagao, Arino Yaguchi and Naoto Morimura

    BMC Anesthesiology 2017 17:59

    Published on: 21 April 2017

  6. Research article

    Effects of short-term hyperoxia on erythropoietin levels and microcirculation in critically Ill patients: a prospective observational pilot study

    The normobaric oxygen paradox states that a short exposure to normobaric hyperoxia followed by rapid return to normoxia creates a condition of ‘relative hypoxia’ which stimulates erythropoietin (EPO) productio...

    Abele Donati, Elisa Damiani, Samuele Zuccari, Roberta Domizi, Claudia Scorcella, Massimo Girardis, Alessia Giulietti, Arianna Vignini, Erica Adrario, Rocco Romano, Laura Mazzanti, Paolo Pelaia and Mervyn Singer

    BMC Anesthesiology 2017 17:49

    Published on: 23 March 2017

  7. Research article

    Continuous Non-invasive finger cuff CareTaker® comparable to invasive intra-arterial pressure in patients undergoing major intra-abdominal surgery

    Despite increased interest in non-invasive arterial pressure monitoring, the majority of commercially available technologies have failed to satisfy the limits established for the validation of automatic arteri...

    Irwin Gratz, Edward Deal, Francis Spitz, Martin Baruch, I. Elaine Allen, Julia E. Seaman, Erin Pukenas and Smith Jean

    BMC Anesthesiology 2017 17:48

    Published on: 21 March 2017

  8. Study protocol

    Midodrine as adjunctive support for treatment of refractory hypotension in the intensive care unit: a multicenter, randomized, placebo controlled trial (the MIDAS trial)

    Patients admitted to intensive care units (ICU) are often treated with intravenous (IV) vasopressors. Persistent hypotension and dependence on IV vasopressors in otherwise resuscitated patients lead to delay i...

    Matthew H. Anstey, Bradley Wibrow, Tharusan Thevathasan, Brigit Roberts, Khushi Chhangani, Pauline Yeung Ng, Alexander Levine, Alan DiBiasio, Todd Sarge and Matthias Eikermann

    BMC Anesthesiology 2017 17:47

    Published on: 21 March 2017

  9. Research article

    A clinical score to predict mortality in septic acute kidney injury patients requiring continuous renal replacement therapy: the HELENICC score

    This study aimed to identify predictors of early (7-day) mortality in patients with septic acute kidney injury (AKI) who required continuous renal replacement therapy (CRRT).

    Rogério da Hora Passos, João Gabriel Rosa Ramos, Evandro Jose Bulhoes Mendonça, Eva Alves Miranda, Fábio Ricardo Dantas Dutra, Maria Fernanda R. Coelho, Andrea C. Pedroza, Luis Claudio L. Correia, Paulo Benigno Pena Batista, Etienne Macedo and Margarida M. D. Dutra

    BMC Anesthesiology 2017 17:21

    Published on: 7 February 2017

  10. Research article

    Acute kidney injury induces high-sensitivity troponin measurement changes after cardiac surgery

    The value of cardiac troponin as a risk assessment tool for cardiac disease in the setting of end-stage renal diseases (ESRD) is not equivalent to its value in those with normal renal function. This considerat...

    Amr S Omar, Khaled Mahmoud, Samy Hanoura, Hany Osman, Praveen Sivadasan, Suraj Sudarsanan, Yasser Shouman, Rajvir Singh and Abdulaziz AlKhulaifi

    BMC Anesthesiology 2017 17:15

    Published on: 31 January 2017

  11. Research article

    Feasibility of the modified sequential organ function assessment score in a resource-constrained setting: a prospective observational study

    Sub-Saharan Africa has a great burden of critical illness with limited health care resources. We evaluated the feasibility and utility of the modified Sequential Organ Function Assessment (mSOFA) score in asse...

    Cornelius Sendagire, Michael S. Lipnick, Sam Kizito, Rebecca Kruisselbrink, Daniel Obua, Joseph Ejoku, Lameck Ssemogerere, Jane Nakibuuka and Arthur Kwizera

    BMC Anesthesiology 2017 17:12

    Published on: 26 January 2017

  12. Research article

    Association between the -159C/T polymorphism in the promoter region of the CD14 gene and sepsis: a meta-analysis

    The association between CD14-159C/T polymorphism and sepsis has been assessed but results of current studies appeared conflicting and inconstant. This analysis was aimed to determine whether the CD14-159C/T po...

    Qin Wu, Xiaomeng Xu, Jianan Ren, Song Liu, Xuelian Liao, Xiuwen Wu, Dong Hu, Gefei Wang, Guosheng Gu, Yan Kang and Jieshou Li

    BMC Anesthesiology 2017 17:11

    Published on: 25 January 2017

  13. Research article

    Clinical usefulness of capnographic monitoring when inserting a feeding tube in critically ill patients: retrospective cohort study

    It is not rare for a small-bore feeding tube to be inserted incorrectly into the respiratory system in critically ill patients. Thus, monitoring is necessary to prevent respiratory malplacement of the tube. We...

    Jeong-Am Ryu, Kyoungjin Choi, Jeong Hoon Yang, Dae-Sang Lee, Gee Young Suh, Kyeongman Jeon, Joongbum Cho, Chi Ryang Chung, Insuk Sohn, Kiyoun Kim and Chi-Min Park

    BMC Anesthesiology 2016 16:122

    Published on: 9 December 2016

  14. Research article

    Human limb skeletal muscle wasting and architectural remodeling during five to ten days intubation and ventilation in critical care – an observational study using ultrasound

    Critically ill patients frequently suffer muscle weakness whilst in critical care. Ultrasound can reliably track loss of muscle size, but also quantifies the arrangement of the muscle fascicles, known as the m...

    Peter Turton, Richard Hay, Jonathon Taylor, Jamie McPhee and Ingeborg Welters

    BMC Anesthesiology 2016 16:119

    Published on: 29 November 2016

  15. Research article

    The incidence of increased ICP in ICU patients with non-traumatic coma as diagnosed by ONSD and CT: a prospective cohort study

    Unexplained coma after critical illness can be multifactorial. We evaluated the diagnostic ability of bedside Optic Nerve Sheath Diameter [ONSD] as a screening test for non-traumatic radiographic cerebral edema.

    Nawal Salahuddin, Alaa Mohamed, Nadia Alharbi, Hamad Ansari, Khaled J. Zaza, Qussay Marashly, Iqbal Hussain, Othman Solaiman, Torbjorn V. Wetterberg and Khalid Maghrabi

    BMC Anesthesiology 2016 16:106

    Published on: 25 October 2016

  16. Research article

    Early antibiotics administration during targeted temperature management after out-of-hospital cardiac arrest: a nationwide database study

    Patients resuscitated after cardiac arrest are reportedly at high risk for infection and sepsis, especially those treated with targeted temperature management (TTM). There is, however, limited evidence suggest...

    Takashi Tagami, Hiroki Matsui, Masamune Kuno, Yuuta Moroe, Junya Kaneko, Kyoko Unemoto, Kiyohide Fushimi and Hideo Yasunaga

    BMC Anesthesiology 2016 16:89

    Published on: 7 October 2016

  17. Research article

    Early prediction of acute kidney injury after transapical and transaortic aortic valve implantation with urinary G1 cell cycle arrest biomarkers

    Acute kidney injury (AKI) is a common complication following transcatheter aortic valve implantation (TAVI) leading to increased mortality and morbidity. Urinary G1 cell cycle arrest proteins TIMP-2 and IGFBP7...

    Fabian Dusse, Michaela Edayadiyil-Dudásova, Matthias Thielmann, Daniel Wendt, Philipp Kahlert, Ender Demircioglu, Heinz Jakob, Simon T Schaefer and Kevin Pilarczyk

    BMC Anesthesiology 2016 16:76

    Published on: 8 September 2016

    The Erratum to this article has been published in BMC Anesthesiology 2016 16:82

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