Critical care

Section edited by Matthias Eikermann

This section deals with all manuscripts related to critical care and ICU medicine.

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  1. Research article

    Association between cardiopulmonary resuscitation duration and one-month neurological outcomes for out-of-hospital cardiac arrest: a prospective cohort study

    The duration of cardiopulmonary resuscitation (CPR) is an important factor associated with the outcomes for an out-of-hospital cardiac arrest. However, the appropriate CPR duration remains unclear considering ...

    Masahiro Kashiura, Yuichi Hamabe, Akiko Akashi, Atsushi Sakurai, Yoshio Tahara, Naohiro Yonemoto, Ken Nagao, Arino Yaguchi and Naoto Morimura

    BMC Anesthesiology 2017 17:59

    Published on: 21 April 2017

  2. Research article

    Effects of short-term hyperoxia on erythropoietin levels and microcirculation in critically Ill patients: a prospective observational pilot study

    The normobaric oxygen paradox states that a short exposure to normobaric hyperoxia followed by rapid return to normoxia creates a condition of ‘relative hypoxia’ which stimulates erythropoietin (EPO) productio...

    Abele Donati, Elisa Damiani, Samuele Zuccari, Roberta Domizi, Claudia Scorcella, Massimo Girardis, Alessia Giulietti, Arianna Vignini, Erica Adrario, Rocco Romano, Laura Mazzanti, Paolo Pelaia and Mervyn Singer

    BMC Anesthesiology 2017 17:49

    Published on: 23 March 2017

  3. Research article

    Continuous Non-invasive finger cuff CareTaker® comparable to invasive intra-arterial pressure in patients undergoing major intra-abdominal surgery

    Despite increased interest in non-invasive arterial pressure monitoring, the majority of commercially available technologies have failed to satisfy the limits established for the validation of automatic arteri...

    Irwin Gratz, Edward Deal, Francis Spitz, Martin Baruch, I. Elaine Allen, Julia E. Seaman, Erin Pukenas and Smith Jean

    BMC Anesthesiology 2017 17:48

    Published on: 21 March 2017

  4. Study protocol

    Midodrine as adjunctive support for treatment of refractory hypotension in the intensive care unit: a multicenter, randomized, placebo controlled trial (the MIDAS trial)

    Patients admitted to intensive care units (ICU) are often treated with intravenous (IV) vasopressors. Persistent hypotension and dependence on IV vasopressors in otherwise resuscitated patients lead to delay i...

    Matthew H. Anstey, Bradley Wibrow, Tharusan Thevathasan, Brigit Roberts, Khushi Chhangani, Pauline Yeung Ng, Alexander Levine, Alan DiBiasio, Todd Sarge and Matthias Eikermann

    BMC Anesthesiology 2017 17:47

    Published on: 21 March 2017

  5. Research article

    A clinical score to predict mortality in septic acute kidney injury patients requiring continuous renal replacement therapy: the HELENICC score

    This study aimed to identify predictors of early (7-day) mortality in patients with septic acute kidney injury (AKI) who required continuous renal replacement therapy (CRRT).

    Rogério da Hora Passos, João Gabriel Rosa Ramos, Evandro Jose Bulhoes Mendonça, Eva Alves Miranda, Fábio Ricardo Dantas Dutra, Maria Fernanda R. Coelho, Andrea C. Pedroza, Luis Claudio L. Correia, Paulo Benigno Pena Batista, Etienne Macedo and Margarida M. D. Dutra

    BMC Anesthesiology 2017 17:21

    Published on: 7 February 2017

  6. Research article

    Acute kidney injury induces high-sensitivity troponin measurement changes after cardiac surgery

    The value of cardiac troponin as a risk assessment tool for cardiac disease in the setting of end-stage renal diseases (ESRD) is not equivalent to its value in those with normal renal function. This considerat...

    Amr S Omar, Khaled Mahmoud, Samy Hanoura, Hany Osman, Praveen Sivadasan, Suraj Sudarsanan, Yasser Shouman, Rajvir Singh and Abdulaziz AlKhulaifi

    BMC Anesthesiology 2017 17:15

    Published on: 31 January 2017

  7. Research article

    Feasibility of the modified sequential organ function assessment score in a resource-constrained setting: a prospective observational study

    Sub-Saharan Africa has a great burden of critical illness with limited health care resources. We evaluated the feasibility and utility of the modified Sequential Organ Function Assessment (mSOFA) score in asse...

    Cornelius Sendagire, Michael S. Lipnick, Sam Kizito, Rebecca Kruisselbrink, Daniel Obua, Joseph Ejoku, Lameck Ssemogerere, Jane Nakibuuka and Arthur Kwizera

    BMC Anesthesiology 2017 17:12

    Published on: 26 January 2017

  8. Research article

    Association between the -159C/T polymorphism in the promoter region of the CD14 gene and sepsis: a meta-analysis

    The association between CD14-159C/T polymorphism and sepsis has been assessed but results of current studies appeared conflicting and inconstant. This analysis was aimed to determine whether the CD14-159C/T po...

    Qin Wu, Xiaomeng Xu, Jianan Ren, Song Liu, Xuelian Liao, Xiuwen Wu, Dong Hu, Gefei Wang, Guosheng Gu, Yan Kang and Jieshou Li

    BMC Anesthesiology 2017 17:11

    Published on: 25 January 2017

  9. Research article

    Clinical usefulness of capnographic monitoring when inserting a feeding tube in critically ill patients: retrospective cohort study

    It is not rare for a small-bore feeding tube to be inserted incorrectly into the respiratory system in critically ill patients. Thus, monitoring is necessary to prevent respiratory malplacement of the tube. We...

    Jeong-Am Ryu, Kyoungjin Choi, Jeong Hoon Yang, Dae-Sang Lee, Gee Young Suh, Kyeongman Jeon, Joongbum Cho, Chi Ryang Chung, Insuk Sohn, Kiyoun Kim and Chi-Min Park

    BMC Anesthesiology 2016 16:122

    Published on: 9 December 2016

  10. Research article

    Human limb skeletal muscle wasting and architectural remodeling during five to ten days intubation and ventilation in critical care – an observational study using ultrasound

    Critically ill patients frequently suffer muscle weakness whilst in critical care. Ultrasound can reliably track loss of muscle size, but also quantifies the arrangement of the muscle fascicles, known as the m...

    Peter Turton, Richard Hay, Jonathon Taylor, Jamie McPhee and Ingeborg Welters

    BMC Anesthesiology 2016 16:119

    Published on: 29 November 2016

  11. Research article

    The incidence of increased ICP in ICU patients with non-traumatic coma as diagnosed by ONSD and CT: a prospective cohort study

    Unexplained coma after critical illness can be multifactorial. We evaluated the diagnostic ability of bedside Optic Nerve Sheath Diameter [ONSD] as a screening test for non-traumatic radiographic cerebral edema.

    Nawal Salahuddin, Alaa Mohamed, Nadia Alharbi, Hamad Ansari, Khaled J. Zaza, Qussay Marashly, Iqbal Hussain, Othman Solaiman, Torbjorn V. Wetterberg and Khalid Maghrabi

    BMC Anesthesiology 2016 16:106

    Published on: 25 October 2016

  12. Research article

    Early antibiotics administration during targeted temperature management after out-of-hospital cardiac arrest: a nationwide database study

    Patients resuscitated after cardiac arrest are reportedly at high risk for infection and sepsis, especially those treated with targeted temperature management (TTM). There is, however, limited evidence suggest...

    Takashi Tagami, Hiroki Matsui, Masamune Kuno, Yuuta Moroe, Junya Kaneko, Kyoko Unemoto, Kiyohide Fushimi and Hideo Yasunaga

    BMC Anesthesiology 2016 16:89

    Published on: 7 October 2016

  13. Research article

    Early prediction of acute kidney injury after transapical and transaortic aortic valve implantation with urinary G1 cell cycle arrest biomarkers

    Acute kidney injury (AKI) is a common complication following transcatheter aortic valve implantation (TAVI) leading to increased mortality and morbidity. Urinary G1 cell cycle arrest proteins TIMP-2 and IGFBP7...

    Fabian Dusse, Michaela Edayadiyil-Dudásova, Matthias Thielmann, Daniel Wendt, Philipp Kahlert, Ender Demircioglu, Heinz Jakob, Simon T Schaefer and Kevin Pilarczyk

    BMC Anesthesiology 2016 16:76

    Published on: 8 September 2016

    The Erratum to this article has been published in BMC Anesthesiology 2016 16:82

  14. Research article

    Lung hyperaeration assessment by computed tomography: correction of reconstruction-induced bias

    Computed tomography (CT) reconstruction parameters, such as slice thickness and convolution kernel, significantly affect the quantification of hyperaerated parenchyma (VHYPER%). The aim of this study was to inves...

    Lorenzo Ball, Claudia Brusasco, Francesco Corradi, Francesco Paparo, Alessandro Garlaschi, Peter Herrmann, Michael Quintel and Paolo Pelosi

    BMC Anesthesiology 2016 16:67

    Published on: 24 August 2016

  15. Research article

    Hypoxia inducible factor-1 alpha and prolinhydroxlase 2 polymorphisms in patients with severe sepsis: a prospective observational trial

    Hypoxia-inducible-factor-1α (HIF-1α) and HIF-1 degrading prolyl-hydroxylases (PHD) are key regulators of the hypoxic-inflammatory response. Functionally active genetic variants in the HIF-1α (C/T; Single Nucleoti...

    Annika Höcker, Miriam Rabeling, Alexandra Bick, Linda Cox, Maximiliane Kreuzer, Andrea Engler, Kai Walstein, Hagen S. Bachmann, Karl-Heinz Jöckel, Lewin Eisele, Michael Adamzik, Jürgen Peters and Simon T. Schäfer

    BMC Anesthesiology 2016 16:61

    Published on: 11 August 2016

  16. Research article

    Phrenic nerve block caused by interscalene brachial plexus block: breathing effects of different sites of injection

    Interscalene brachial plexus (ISB) block is often associated with phrenic nerve block and diaphragmatic paresis. The goal of our study was to test if the anterior or the posterior ultrasound guided approach of...

    Lars Bergmann, Stefan Martini, Miriam Kesselmeier, Wolf Armbruster, Thomas Notheisen, Michael Adamzik and Rϋdiger Eichholz

    BMC Anesthesiology 2016 16:45

    Published on: 29 July 2016

  17. Research article

    Prognostic significance of APACHE II score and plasma suPAR in Chinese patients with sepsis: a prospective observational study

    Timely risk stratification is the key strategy to improve prognosis of patients with sepsis. Previous study has proposed to develop a powerful risk assessment rule by the combination of Acute Physiology and Ch...

    Xuan Liu, Yong Shen, Zhihua Li, Aihua Fei, Hairong Wang, Qinmin Ge and Shuming Pan

    BMC Anesthesiology 2016 16:46

    Published on: 29 July 2016

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